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Term Framework for the Provision of Chemistry Synthesis and other Chemistry Services Outsourcing Framework

University of Dundee Published 29 Nov 2024 Public Contracts Scotland
The value below is a framework or dynamic market ceiling: the maximum that could be spent across all call-offs, not the value of a single contract. Aggregate figures on this site exclude these to avoid double counting.

key details

Value£4,000,000
Statuscomplete
Category (CPV) 73110000
RegionScotland
Deadline26 Apr 2024
Procedureopen
OCIDocds-h6vhtk-044ba4

Awards (11)

This procurement was awarded to 11 suppliers. Values shown are per-award; the notice total is £4,000,000.

SupplierValueDateStatus
3xper Innoventure Limited shared · · ·
BioAscent Discovery Ltd shared · · ·
Cambridge Bioscience shared · · ·
ChemPartner Europe ApS shared · · active
Chemveda Life Sciences India Pvt. Ltd. shared · · active
"ENAMINE" SIA shared · · ·
Jubilant Biosys Limited shared · · active
Sai Life Sciences shared · · ·
SYNGENE INTERNATIONAL LIMITED shared · · ·
TCG Lifesciences shared · · ·
WuXi Apptec shared · · active

description

Second-Generation Framework for the provision of Chemistry Synthesis and other Chemistry Services Outsourcing with initial term of two (2) years with the option to extend for up to 2 x 12 months, if required, at the sole discretion of the University and subject to ongoing satisfactory performance by the appointed Service Providers.

The Services will include:

  1. FTE rate for provision of chemistry support for medicinal chemistry programme(s), typically making 50mg samples of compounds for initial biological evaluation. For actives, re-synthesis on a larger scale may be required (typically 0.5g to 5g scale). The ability to carry out array chemistry is important;

2.Bespoke piece(s) of chemistry e.g. synthesis of a defined list of compounds, typically at <50mg scale;

  1. Scale up of chemistry, up to 200g;

4.Chiral separation by crystallization or SFC/Chiral HPLC on (up to) gram scale.

5.Synthesis of intermediates at 5-100g;

For all of these, a purity level will be defined. This will depend on the phase of the project, but typically is >95% purity and for scale up> 98% purity with no impurity >0.5%;

  1. Experimental write-ups, when requested, including compound characterization by 1H NMR, 13C NMR and LCMS or UPLC/MS for publications, in-vivo release, tech-transfer to DDU or other CRO for patent purposes.

documents

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notice history

7 notices published against this procurement.

PublishedTypeRegimeNotice
22 Mar 2024 Contract notice (F02) Earlier regulations 009350-2024
5 Apr 2024 Corrigendum (F14) Earlier regulations 011134-2024
17 Apr 2024 Corrigendum (F14) Earlier regulations 012436-2024
7 May 2024 Corrigendum (F14) Earlier regulations 014528-2024
13 May 2024 Corrigendum (F14) Earlier regulations 015084-2024
26 Nov 2024 Contract award notice (F03) Earlier regulations 038232-2024
29 Nov 2024 Modification notice (F20) Earlier regulations 038621-2024

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source

Published on Public Contracts Scotland. Contact details for named individuals are not reproduced on this site.