LUV01414 Purchase of C Trap Dymo 400 by direct award

The University of Leicester, School of Chemistry, is expanding its capabilities for studying the dynamics of single biomolecules. To support this work, funding has been secured from BBSRC to procure a highly specialised instrument: the C-Trap Dymo 400 Optical Tweezers-Fluorescence Microscope, manufactured by Lumicks B.V.. This instrument integrates cutting-edge optical trapping, confocal fluorescence microscopy, and laminar flow microfluidics into a single, coherent system.

The C-Trap® Dymo 400 will be installed at the University to support high-precision, realtime studies of molecular interactions, particularly in areas involving DNA-protein complexes, RNA structures, ubiquitin structures and cytoskeletal filament dynamics. It includes multi-colour confocal fluorescence (488, 561, 638 nm), dual force detection (x,y), short tether capabilities, microfluidics, and full system integration with proprietary Bluelake software, all required to maintain the scientific edge of our ongoing biophysical and molecular biology research.

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