RFQ Awarded - Preparative HPLC
key details
| Status | complete |
|---|---|
| Category (CPV) | 38000000 |
| Region | London |
| Deadline | 6 Nov 2020 |
| Contract start | 11 Jan 2021 |
| Contract end | 10 Jan 2022 |
| Procedure | limited |
| SME suitable | Yes |
| OCID | ocds-b5fd17-99c55ccf-4aec-4043-ab96-dd99018a8b8b |
Award
| Supplier | Value | Date | Status |
|---|---|---|---|
| Waters Ltd | £52,629 | 17 Dec 2020 | active |
description
The National Physical Laboratory (NPL) requires automation to facilitate the purification of peptides which have been synthesized via 9-Fluorenylmethoxycarbonyl (Fmoc) Solid Phase Peptide Synthesis (SPPS). Due to the intrinsic nature of this synthetic technique, it is quite common to isolate crude peptides as a mixture of the desired product and closely related impurities (e.g. protecting group adducts / deletion sequences).
NPL tends to synthesize difficult peptides (self assembling, repeating motifs, slightly insoluble sequences) on 0.1 mmol scale via microwave assisted Fmoc SPPS; yielding 150 mg to 400 mg of crude product after resin cleavage. NPL is seeking to purchase a preparative HPLC, which will facilitate the purification of larger quantities of crude peptide per run (than we are currently able, i.e. >> 15-20 mg per un); and therefore yield greater quantities of highly pure peptides.
notice history
1 notice published against this procurement.
| Published | Type | Regime | Notice |
|---|---|---|---|
| 13 Jan 2021 | Award (award) | · | eec02384-8310-475c-b473-8289a70ca29e-405387 |
more from National Physical Laboratory
- Strategic Reporting · £500,000 · 16 Jun 2025
- RFQ_128032 - Bibliometric Assessment of the National Physical Laboratory's (NPL) Research Output · £40,750 · 18 Feb 2025
- Study on Better Evidencing Benefits Attributable to NPL's Work in Radiotherapy · £60,000 · 18 Feb 2025
- ITT_129557 - Evaluation of the National Timing Centre R&D Programme (2019-25) · £130,000 · 14 Feb 2025
- Cryogen Free JJ Volt System · £350,000 · 27 Jan 2025
- ITT_123111 - Cryogen Free Josephson Junction (JJ) Voltage System · £350,000 · 27 Jan 2025
- RFQ - BioCentrifuge and Rotors 129563 · 20 Jan 2025
- Laboratory building construction work (Building 47) for the National Physical Laboratory · £5,000,000 · 13 Dec 2024
all contracts from this buyer →
similar contracts awarded
Other awarded contracts in the same category. Useful for seeing who normally wins this kind of work, and at what value.
- The Provision of a MSC Class II Cabinet · Medicines and Healthcare Products Regulatory Agency · £17,718
- NCA31153 Incucyte SX5 (for IRR South) · University Of Edinburgh · £220,990
- Cryogenic System · University of Bristol · £215,775
- Supply and Support of Automated Film Scanners · Historic Environment Scotland · £190,000
- 4998/AM/GM - Digital Product Passport Cell R3 · UNIVERSITY OF SHEFFIELD · £400,000
- Underwater Cameras for FloWave · University Of Edinburgh · £63,302
- Cytation 9 Imager and 406 FX Washer and Reagent Dispenser · University Of Edinburgh · £195,000
- Procurement of Pilot Freeze Dryer · MHRA · £200,000
source
Published on Contracts Finder. Contact details for named individuals are not reproduced on this site.