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Generation of homozygous transgenic mice from hemizygous cryopreserved embryos

Defra Network eTendering Portal Published 30 Sept 2022 Contracts Finder

key details

Value£37,556
Statuscomplete
Category (CPV) 71900000
RegionSouth East
Deadline1 Jul 2022
Contract start1 Oct 2022
Contract end31 Jul 2025
Proceduredirect
SME suitableYes
OCIDocds-b5fd17-16d561c7-213c-4907-bd1e-862d4aa24b4f

Award

SupplierValueDateStatus
Charles River Laboratories Ltd £54,764 29 Sept 2022 active

description

APHA require the production of a lineage of mice (mus musculus) which are homozygous for a bank-vole (Myodes glareolus) prion transgene. Prions cause transmissible spongiform encephalopathies (TSEs) such as mad cow disease in cattle which is associated with variant CJD in humans. Animal TSEs are fatal and can be zoonotic i.e. can transmit from animals to human. Rodents are used for characterising these diseases and defining their zoonotic potential.

Additional information:

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notice history

1 notice published against this procurement.

PublishedTypeRegimeNotice
30 Sept 2022 Award (award) · eee883ec-e344-473f-85f5-0c47f6df4c44-576648

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