MIROCALS Study Flow cytometry cell subset numeration in human whole blood and monitoring of pNF-H in CSF and plasma samples by ELISA
key details
| Status | active |
|---|---|
| Category (CPV) | 73111000 |
| Region | South East |
| Deadline | 19 Aug 2016 |
| Contract start | 19 Sept 2016 |
| Contract end | 18 Sept 2018 |
| Procedure | open |
| SME suitable | No |
| OCID | ocds-b5fd17-ed227063-adc9-11e6-9901-0019b9f3037b |
description
The Service Provider is requested to monitor the absolute number and frequency of circulating white blood cell subsets including FOXP3+ regulatory T cells (Tregs), CD3+, CD4+, CD8+, B, and NK cells in EDTA whole blood samples and the circulating pNF-H biomarker in CSF and plasma.
For whole blood samples, cell subsets should be analysed by flow cytometry. There will be 216 patients and 5 time points per patient (1080 samples in total).
For plasma and CSF samples, the pNF-H should be monitored using a commercial ELISA kit (Biovendor). There will be 3 plasma samples + 3 CSF samples per patient from 216 patients (2 x 3 x 216 = 1296 samples in total.
All procedures will need to be validated, including the preanalytical stability of whole blood samples prior to flow cytometry analysis.
Additional information: Is a Recurrent Procurement Type? : No https://in-tendhost.co.uk/universityofsussex/aspx/
documents
- https://in-tendhost.co.uk/universityofsussex/aspx/ , tenderNotice
- https://www.contractsfinder.service.gov.uk/Notice/b5853e3b-3e8f-4274-85cb-4acecc067b03 , tenderNotice
Documents are linked, not mirrored. They are served by the publishing authority and may require registration.
notice history
1 notice published against this procurement.
| Published | Type | Regime | Notice |
|---|---|---|---|
| 18 Nov 2016 | Tender (tender) | · | b5853e3b-3e8f-4274-85cb-4acecc067b03-103313 |
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source
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