Human Normal Intravenous Immunoglobulin Evidence Reviews

The Blood and Infection Programme of Care is seeking support for it Immunoglobulin Improving Value Project.

Immunoglobulin is commissioned by NHS England in line with Department of Health Clinical guidelines for immunoglobulin use.

https://www.gov.uk/government/publications/clinical-guidelines-for-immunoglobulin-use-second-edition-update

The guidelines state which conditions immunoglobulin is recommended for and these are colour coded according to priority. A red classification indicates the highest priority as there could be a risk to life without treatment. A blue classification is for those indications where there is some evidence of benefit but for which there may be alternative treatments and for which treatment may be modified in times of supply shortages of immunoglobulin. Grey indications are those for which the evidence is weak, including rare disorders.

It is envisaged that the successful organisation will be able to provide the required clinical evidence reviews to meet our objectives of providing safe, effective, evidence based care and will have the relevant experience, knowledge and capability to carry out detailed clinical evidence reviews for the grey indications from the Clinical Guidelines for Immunoglobulin Use 2nd edition.

It is expected the chosen provider will be able to carry out the following:

Scoping reviews to identify literature reporting on the use of immunoglobulin, in people with a grey indication. It would include a scoping of the literature to:

Then provide rapid reviews for those indications where there are experimental controlled trials or observational studies with a control group including:

Please note that that this contract may be extended for an additional 3 months.

Interested parties must be registered on Bravo Solutions in order to access the ITT documents. Please use the following address if you are not already registered: https://nhsengland.bravosolution.co.uk/web/login.html.

IN ADDITION, PLEASE ENSURE YOU EMAIL VANESSA.AMISSAH@NHS.NET TO EXPRESS AN INTEREST BY FRIDAY 12TH JANUARY 2018, 12 NOON, AT THE LATEST. IT IS ENVISAGED THAT THE INVITATION TO TENDER DOCUMENTS WILL BE MADE AVAILABLE BY MID-LATE JANUARY 2018.