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ECIS Equipment - UOE/2017/064/WH

University of Exeter Published 26 Apr 2018 Contracts Finder

key details

Value£71,000
Statuscomplete
Category (CPV) 38000000
RegionSouth West
Deadline18 Apr 2018
Contract start19 Apr 2018
Contract end20 Apr 2018
Procedureopen
SME suitableYes
OCIDocds-b5fd17-5047fb90-d637-4122-afcc-244e0fbe8f30

Award

SupplierValueDateStatus
bidi GmbH £58,000 23 Apr 2018 active

description

Endothelial cell barrier function measurements: Endothelial cells (ECs) play a key role in the cerebrovasculature in maintaining the blood brain barrier (BBB). ECs line the walls of the blood vessels and act as a selective barrier to regulate the passage of fluids, macromolecules, hormones and leukocytes from the vascular space to the interstitium. Our preliminary data indicates that structural alterations of ECs in vitro results in plasma protein leakage and leukocyte extravasation which lead to inflammation.

We have recently received a grant from Alzheimer's Research UK (ARUK) allowing us to invest in a label free, non- invasive and automated instrument that will allow monitoring EC behaviour in real- time.

Essential features of the instrument must include:

The ability to perform experiments in controlled gas environments in existing incubators
Cells to be grown on electrodes with multi-well (8, 16 or 96) configuration
Computer and an integrated software gathering data and analysis (Windows / MAC compatible)
The ability to measure impedance in a range of frequencies (low to high)
The ability to perform measurements under flow conditions (to mimic shear stress on ECs in vivo)
Training, warranty and service contract
Consumables (10 experiments: 10 x 8 Well Arrays

documents

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notice history

2 notices published against this procurement.

PublishedTypeRegimeNotice
26 Mar 2018 Tender (tender) · 56574cdb-c32e-4722-b219-67a31e042494-207581
26 Apr 2018 Award (award) · 748feac9-1037-4b93-a0d7-281d8cd52a22-213159

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