Q Fever collection of patient serum
key details
| Status | planning |
|---|---|
| Category (CPV) | 33124000 +8 more |
| Region | East of England |
| SME suitable | No |
| OCID | ocds-b5fd17-3da44687-ed61-4130-bc6f-627217002010 |
description
The agency is planning to establish a human reference serum containing anti-C. burnetii IgG and IgM antibodies, with the objective to validate this material as a WHO international standard. To establish this human reference serum, we require the collection of serum that meets the inclusion criteria detailed below. Suppliers that can meet the requirements below are invited to register their interest for the supply and testing of serum samples for the development of a WHO standard for Q fever. Suppliers must be able to:
| 1. | Evaluate the exact requirements for the development of a WHO standard for Q fever. To enable this in a timely fashion, the supplier should have an established network in the Q fever community to engage with |
| 2. | Identify subjects with different stages of Q fever infection (convalescing, actively infected or very recent (chronic) infection) |
| 3. | Access a large collection of banked samples from a well characterised cohort of past Q fever (exposed) patients for selection of convalescing subjects |
| 4. | Actively recruit subjects with active or very recent infection (unless already identified through recent/ongoing efforts) |
| 5. | Selected subjects should be aware that serum may be characterised and evaluated in an in vivo potency model for experimental vaccines. |
| 6. | Re-test /verify sero-positivity in selected patient to ensure fitness for purpose for this study (seropositivity confirmed by the most commonly used laboratory assays (IFA, ELISA, CFT) |
| 7. | Characterize donors with independent measures (other than serology) for confirmation of exposure to C. burnetii, such as PCR, IGRA or testing for cellular recall responses |
| 8. | Select at least 5 appropriate donors (defined in the evaluation) for large volume serum collection |
| 9. | Arrange plasmapheresis of the 5 donors |
| 10. | Prepare serum from donor samples |
| 11. | Test/arrange testing of serum samples for blood borne pathogens (HIV, HBV and HCV) |
| 12. | Supply NIBSC with a small sample, 25mL, for additional testing |
| 13. | Ship 500 ml serum samples from each donor to NIBSC |
The supplier should have the capability of supplying the collected and tested Q fever seropositive samples within 6 months of establishing the requirements.
As far as we are aware there is only one supplier who is able to meet this very specific request. Potential suppliers if they feel they can meet the requirement should email Nawaz.habib@nibsc.org to register an interest.
If no submissions of potential interest are received by close of play 5th April 2019, it is then intended to perform a direct award without competition to the sole supplier we believe can deliver the required service.
notice history
1 notice published against this procurement.
| Published | Type | Regime | Notice |
|---|---|---|---|
| 15 Mar 2019 | Planning (planning) | · | 1840c47d-5fc1-4c3f-9b96-26151d7f005c-276289 |
more from MHRA Buyer Organisation
- ELISpot-FLUOROSpot reader · £50,000 · 2 Dec 2022
- Isothermal Titration Calorimeter (C104655) · £60,000 · 25 Nov 2022
- Purchase of Monoclonal Antibodies · £500,000 · 21 Oct 2022
- Purchase of a mid-throughput DNA genotyping analysis system · £100,000 · 12 Oct 2022
- Automated Sample Preparation (bead based system) · £200,000 · 5 Oct 2022
- C30693_Lot 2_Bedding for BSD · £80,000 · 19 Aug 2022
- C30693_Diet for BSD_L0t 1 · £100,000 · 19 Aug 2022
- Fluorescence Plate Reader · £50,000 · 8 Aug 2022
all contracts from this buyer →
similar contracts awarded
Other awarded contracts in the same category. Useful for seeing who normally wins this kind of work, and at what value.
- RBC Contract for Keyfax Repairs Diagnostics and Repairs Self-Service with KeyNect · Redditch Borough Council
- Staffed, mobile PET-CT at PRH · University Hospitals Sussex NHS Foundation Trust · £43,680
- Radiology Reporting · Nottingham University Hospitals · £1,093,869
- Dexa Bone Scanner · The Newcastle Upon Tyne Hospitals NHS Foundation Trust · £89,880
- Radiology Reporting Out of Hours · Dorset County Hospital NHS Foundation Trust · £1,260,000
- Cardiac MRI scanning · University Hospitals Sussex NHS Foundation Trust · £197,461
- GB-Kettering Northants: Managed Service CT & MRI Community Diagnostic Centres for Kettering General Hospital NHS Foundation Trust and Northampton General Hospital NHS Trust · Kettering General Hospital NHS Foundation Trust · £30,000,000
- Ultima cardio2 Cardiorespiratory Diagnostic Systems · University Of The West Of England · £61,584
source
Published on Contracts Finder. Contact details for named individuals are not reproduced on this site.